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Current position:Home > Products > Phenformin

CAS No.:114-86-3

Name: Phenformin

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 subcutaneous 16mg/kg (16mg/kg)   Medicina Experimentalis. Vol. 8, Pg. 237, 1963.
guinea pig LDLo intravenous 30mg/kg (30mg/kg)   "Hemoperfusion: Kidney and Liver Support and Detoxification, Proceedings of the International Symposium, Haifa, 1979," Sideman, S., and T.M.S. Chang, eds., Multiple parts, New York, Hemisphere Pub. Corp., 1980-Vol. 1, Pg. 337, 1980.
mouse LD50 intraperitoneal 140mg/kg (140mg/kg)   Bollettino Chimico Farmaceutico. Vol. 97, Pg. 396, 1958.
mouse LD50 oral 450mg/kg (450mg/kg)   Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 42, Pg. 236, 1985.
rat LD50 oral 650mg/kg (650mg/kg)   Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 42, Pg. 236, 1985.


Consensus Reports:

 


SAFETY PROFILE:

Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.Safety information of Phenformin (CAS NO.114-86-3):
Hazard Codes: HarmfulXn
Risk Statements: 22
R22:Harmful if swallowed.
Safety Statements: 36
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: DU2200000


Standards and Recommendations:

 


Analytical Methods:

 


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