CAS No.:50-34-0

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LDLo	intravenous	51mg/kg (51mg/kg)		Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 151, Pg. 614, 1957.
mouse	LD50	intraperitoneal	60mg/kg (60mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 326, 1969.
mouse	LD50	intravenous	6400ug/kg (6.4mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ATAXIA	Toxicology and Applied Pharmacology. Vol. 1, Pg. 391, 1959.
mouse	LD50	oral	445mg/kg (445mg/kg)		Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 319, 1970.
mouse	LD50	subcutaneous	128mg/kg (128mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 326, 1969.
rabbit	LD50	oral	750mg/kg (750mg/kg)		Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 36, 1973.
rat	LD50	intraduodenal	125mg/kg (125mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
rat	LD50	intraperitoneal	25mg/kg (25mg/kg)		Compilation of LD50 Values of New Drugs.
rat	LD50	intravenous	4mg/kg (4mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Toxicology and Applied Pharmacology. Vol. 1, Pg. 391, 1959.
rat	LD50	oral	370mg/kg (370mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
rat	LD50	subcutaneous	298mg/kg (298mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.

RTECS:  BP8249200

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes:  Xn
Risk Statements:  22 (R22:Harmful if swallowed.)
Safety Statements:  36 (S36:Wear suitable protective clothing.)

Standards and Recommendations：

 

Analytical Methods：