CAS No.:603-00-9

TOXICITY DATA with REFERENCE：

1.		orl-rat LD50:460 mg/kg		OYYAA2    Oyo Yakuri. Pharmacometrics. 19 (1980),845.
2.		ipr-rat LD50:445 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),720.
3.		ivn-rat LD50:430 mg/kg		OYYAA2    Oyo Yakuri. Pharmacometrics. 19 (1980),845.
4.		orl-mus LD50:730 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),720.
5.		ipr-mus LD50:505 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),14.
6.		scu-mus LD50:410 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 4 (1954),649.
7.		ivn-mus LD50:475 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),720.

Consensus Reports：

 

SAFETY PROFILE：

Moderately toxic by ingestion, intraperitoneal, subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x. See also THEOPHYLLINE.
Hazard Codes:
Xn: Harmful
Risk Statements about β-Hydroxypropyltheophylline (603-00-9):
R22 Harmful if swallowed.
Safety Statements about β-Hydroxypropyltheophylline (603-00-9):
S36 Wear suitable protective clothing.

Standards and Recommendations：

 

Analytical Methods：