CAS No.:87-66-1

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	75mg/kg (75mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
dog	LDLo	intravenous	80mg/kg (80mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 254, 1955.
dog	LDLo	oral	25mg/kg (25mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 254, 1955.
dog	LDLo	subcutaneous	300mg/kg (300mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 254, 1955.
frog	LDLo	subcutaneous	200mg/kg (200mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA	Revue Medicale de la Suisse Romande. Vol. 15, Pg. 561, 1895.
human	LDLo	oral	28mg/kg (28mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: OTHER CHANGES	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 507, 1969.
man	LDLo	subcutaneous	120mg/kg (120mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Znetralbaltt fuer die Medizinischen Wissenschaften. Vol. 19, Pg. 545, 1881.
mouse	LD50	intraperitoneal	400mg/kg (400mg/kg)		National Technical Information Service. Vol. AD691-490,
mouse	LD50	oral	300mg/kg (300mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(8), Pg. 6, 1973.
mouse	LD50	subcutaneous	566mg/kg (566mg/kg)		Zeitschrift fuer die Gesamte Innere Medizin und Ihre Grenzgebiete. Vol. 2, Pg. 333, 1947.
rabbit	LD50	oral	1600mg/kg (1600mg/kg)	GASTROINTESTINAL: GASTRITIS LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA	American Journal of Veterinary Research. Vol. 23, Pg. 1264, 1962.
rabbit	LDLo	subcutaneous	1gm/kg (1000mg/kg)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat	LDLo	subcutaneous	650mg/kg (650mg/kg)		Journal of Agricultural and Food Chemistry. Vol. 17, Pg. 497, 1969.

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes: Xn
Risk Statements: 20/21/22-52/53-68-40 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R68:Possible risk of irreversible effects. 
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 22-24/25-61-36/37 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets. 
S36/37:Wear suitable protective clothing and gloves.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: UX2800000
F: 8
HazardClass: 6.1
PackingGroup: III

Standards and Recommendations：

 

Analytical Methods：