CAS No.:36735-22-5

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD	oral	> 1gm/kg (1000mg/kg)	BEHAVIORAL: ATAXIA BEHAVIORAL: ANALGESIA	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 1456, 1982.
dog	LD	oral	> 1gm/kg (1000mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 37, Pg. 906, 1987.
mouse	LD50	intraperitoneal	845mg/kg (845mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Arzneimittel-Forschung. Drug Research. Vol. 37, Pg. 906, 1987.
mouse	LDLo	oral	5gm/kg (5000mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 1456, 1982.
rat	LD50	intraperitoneal	2749mg/kg (2749mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Arzneimittel-Forschung. Drug Research. Vol. 37, Pg. 906, 1987.
rat	LD50	oral	> 5gm/kg (5000mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 37, Pg. 906, 1987.

Consensus Reports：

 

SAFETY PROFILE：

Safety information of 2H-1,4-Benzodiazepine-2-thione, 7-chloro-5- (2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)- (36735-22-5):
RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III

Standards and Recommendations：

 

Analytical Methods：