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CAS No.:132-27-4

Name: Sodium 2-biphenylate

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Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 500mg/kg (500mg/kg)   FAO Nutrition Meetings Report Series. Vol. 38A, Pg. 47, 1965.
mouse LD50 oral 683mg/kg (683mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 30, Pg. 54, 1979.
rat LD50 oral 656mg/kg (656mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: RELAXATION (ISOLATED TISSUE)
Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 30, Pg. 57, 1979.


Consensus Reports:

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon. France.: ) (single copies can be ordered from WHO Publications centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 30 (1983),p. 329.(World Health Organization, Internation Agency for Research on Cancer,Lyon. France.: ) (single copies can be ordered from WHO Publications centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. A human skin irritant. A severe skin irritant to experimental animals. When heated to decomposition it emits toxic fumes of Na2O. 
Hazard Codes: HarmfulXn,DangerousN
Risk Statements: 22-37/38-41-50
 R22:Harmful if swallowed. 
R37/38:Irritating to respiratory system and skin. 
R41:Risk of serious damage to the eyes. 
R50:Very toxic to aquatic organisms.
Safety Statements: 22-26-61 
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: DV7750000
HazardClass: 8
PackingGroup of 2-Biphenylol sodium salt (CAS NO.132-27-4): III


Standards and Recommendations:

 


Analytical Methods:

 


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