CAS No.:85622-93-1

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LDLo	intraperitoneal	125mg/kg (125mg/kg)		Cancer Research. Vol. 47, Pg. 5846, 1987.

Consensus Reports：

 

SAFETY PROFILE：

Safety Information about Temozolomide (CAS NO.85622-93-1):
Hazard Codes:  T,  Xi
The Risk Statements: 45-46-60-61-22-36/37/38
45: May cause cancer 
46: May cause heritable genetic damage 
60: May impair fertility 
61: May cause harm to the unborn child 
36/37/38: Irritating to eyes, respiratory system and skin 
The Safety Statements: 24/25-45-36/37-26-53
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)  
53: Avoid exposure - obtain special instruction before use 
24/25: Avoid contact with skin and eyes 
36/37: Wear suitable protective clothing and gloves 

Standards and Recommendations：

 

Analytical Methods：

Laboratory studies and clinical trials are investigating whether it might be possible to further increase the anticancer potency of temozolomide by combining it with other pharmacologic agents.