CAS No.:97322-87-7
Name: Troglitazone
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| monkey | LD50 | oral | > 2gm/kg (2000mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 38, Pg. 1121, 1996. | |
| mouse | LD | oral | > 300mg/kg (300mg/kg) | European Patent Application. Vol. #439321, | |
| mouse | LD50 | intraperitoneal | > 5gm/kg (5000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995. | |
| mouse | LD50 | intravenous | 42mg/kg (42mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967. | |
| rat | LD50 | intraperitoneal | > 4gm/kg (4000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995. | |
| rat | LD50 | oral | > 5gm/kg (5000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995. | |
| women | TDLo | oral | 840mg/kg/15W- (840mg/kg) | BRAIN AND COVERINGS: ENCEPHALITIS LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" |
Annals of Internal Medicine. Vol. 129, Pg. 98, 1998. |
Consensus Reports:
SAFETY PROFILE:
Safety Information of Troglitazone (CAS NO.97322-87-7):
Safety Statements: 22-24/25
22: Do not breathe dust
24: Avoid contact with skin
25: Avoid contact with eyes
Standards and Recommendations:
Analytical Methods:
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