CAS No.:61-80-3

TOXICITY DATA with REFERENCE：

1.		orl-hmn TDLo:14 mg/kg/D:CNS		JAMAAP    JAMA, Journal of the American Medical Association. 160 (1956),745.
2.		orl-rat LD50:782 mg/kg		FEPRA7    Federation Proceedings, Federation of American Societies for Experimental Biology. 16 (1957),319.
3.		ipr-rat LD50:102 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 129 (1960),75.
4.		orl-mus LD50:540 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 128 (1960),112.
5.		ipr-mus LD50:100 mg/kg		NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 .
6.		ivn-mus LD50:376 mg/kg		29QHAQ    Principles of Medicinal Chemistry Foye, W.O., eds.,Philadelphia, PA.: Lea and Febiger,1974,74.
7.		ivn-dog LD50:117 mg/kg		FEPRA7    Federation Proceedings, Federation of American Societies for Experimental Biology. 16 (1957),319.
8.		orl-ham LD50:670 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 129 (1960),75.
9.		ipr-ham LD50:268 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 129 (1960),75.

Carcinogenicity of 2-Amino-5-chlorobenzoxazole (CAS.61-80-3) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. You can see actual entry in RTECS for complete information.

Consensus Reports：

 

SAFETY PROFILE：

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: muscle rigidity. When heated to decomposition it yields toxic fumes of Cl⁻ and NO_x.
 

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.

Standards and Recommendations：

 

Analytical Methods：