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Current position:Home > Products > 1-(2-(Diethylamino)ethyl)-2-((p-ethoxy-phenyl)thio)benzimidazole hydrochloride

CAS No.:4929-77-5

Name: 1-(2-(Diethylamino)ethyl)-2-((p-ethoxy-phenyl)thio)benzimidazole hydrochloride

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 84mg/kg (84mg/kg) BEHAVIORAL: ANALGESIA Yakugaku Zasshi. Journal of Pharmacy. Vol. 85, Pg. 962, 1965.
mouse LD50 intravenous 24mg/kg (24mg/kg) BEHAVIORAL: ANALGESIA

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Yakugaku Zasshi. Journal of Pharmacy. Vol. 87, Pg. 296, 1967.
mouse LD50 oral 230mg/kg (230mg/kg) BEHAVIORAL: ANALGESIA

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Yakugaku Zasshi. Journal of Pharmacy. Vol. 87, Pg. 296, 1967.
mouse LD50 subcutaneous 190mg/kg (190mg/kg) BEHAVIORAL: ANALGESIA

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Yakugaku Zasshi. Journal of Pharmacy. Vol. 87, Pg. 296, 1967.


Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of SOx, NOx, and HCl.


Standards and Recommendations:

 


Analytical Methods:

 


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