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Current position:Home > Products > 1-(2-CHLOROETHYL)-3-(2-HYDROXYETHYL)-1-NITROSOUREA

CAS No.:60784-46-5

Name: 1-(2-CHLOROETHYL)-3-(2-HYDROXYETHYL)-1-NITROSOUREA

Details Introduction

TOXICITY DATA with REFERENCE:

1.   

sln-dmg-orl 5 mmol/L

    DRISAA    Drosophila Information Service. 52 (1977),20.
2.   

sln-dmg-par 5 mmol/L

    DRISAA    Drosophila Information Service. 52 (1977),20.
3.   

mrc-smc 1 mmol/L/16H

    MUREAV    Mutation Research. 42 (1977),45.
4.   

dnd-rat-ipr 100 µmol/kg

    CNREA8    Cancer Research. 44 (1984),514.
5.   

cyt-mus:lng 1 mg/L/1H

    MUREAV    Mutation Research. 44 (1977),87.
6.   

ivn-rat TDLo:16 mg/kg/60W-I:ETA

    DTESD7    Developments in Toxicology and Environmental Science. 8 (1980),273.
7.   

ipr-rat LD50:25,300 µg/kg

    ONCOBS    Oncology. 37 (1980),177.
8.   

ipr-mus LD50:25 mg/kg

    INSSDM    INSERM Symposium. 19 (1981),123.

Consensus Reports:EPA Genetic Toxicology Program.
SAFETY PROFILE:
Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of Cl and NOx. See also N-NITROSO COMPOUNDS.

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