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CAS No.:99464-64-9

Name: Ampiroxicam

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Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
monkey LD50 oral > 500mg/kg (500mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 36, Pg. 432, 1994.
mouse LD50 intraperitoneal 1358mg/kg (1358mg/kg)   Drugs in Japan Vol. -, Pg. 119, 1995.
mouse LD50 oral 2291mg/kg (2291mg/kg)   Drugs in Japan Vol. -, Pg. 119, 1995.
mouse LD50 subcutaneous 4259mg/kg (4259mg/kg)   Drugs in Japan Vol. -, Pg. 119, 1995.
rat LD50 intraperitoneal 282mg/kg (282mg/kg)   Drugs in Japan Vol. -, Pg. 119, 1995.
rat LD50 oral 747mg/kg (747mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
KIDNEY, URETER, AND BLADDER: INCONTINENCE
Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 1, 1992.
rat LD50 subcutaneous 2598mg/kg (2598mg/kg)   Drugs in Japan Vol. -, Pg. 119, 1995.


Consensus Reports:

 


SAFETY PROFILE:

 


Standards and Recommendations:

 


Analytical Methods:

 


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