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CAS No.:339-43-5

Name: Benzenesulfonamide, 4-amino-N-((butylamino)carbonyl)-

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Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 250mg/kg (250mg/kg)   National Technical Information Service. Vol. AD691-490,
mouse LD50 intravenous 1920mg/kg (1920mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Diabetes. Vol. 6, Pg. 2, 1957.
mouse LD50 oral 2800mg/kg (2800mg/kg)   Farmakologiya i Toksikologiya Vol. 25, Pg. 93, 1962.
mouse LD50 subcutaneous 2640mg/kg (2640mg/kg)   Diabetes. Vol. 6, Pg. 2, 1957.
rat LD50 intravenous 980mg/kg (980mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Diabetes. Vol. 6, Pg. 2, 1957.
rat LD50 oral 4400mg/kg (4400mg/kg)   French Demande Patent Document. Vol. #2390165,


Consensus Reports:

Reported in EPA TSCA Inventory.


SAFETY PROFILE:

A poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and SOx.


Standards and Recommendations:

 


Analytical Methods:

 


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