CAS No.:124-63-0
Name: Methanesulfonyl chloride
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | skin | 100uL/kg (0.1mL/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | National Technical Information Service. Vol. OTS0571119, |
mouse | LD50 | intraperitoneal | 10mg/kg (10mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA |
National Technical Information Service. Vol. OTS0571119, |
mouse | LD50 | oral | 200mg/kg (200mg/kg) | KIDNEY, URETER, AND BLADDER: HEMATURIA | National Technical Information Service. Vol. OTS0571119, |
rat | LCLo | inhalation | 620mg/m3/6H (620mg/m3) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
National Technical Information Service. Vol. OTS0571119, |
rat | LD50 | oral | 50mg/kg (50mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD KIDNEY, URETER, AND BLADDER: HEMATURIA |
National Technical Information Service. Vol. OTS0571119, |
rat | LDLo | intraperitoneal | 5mg/kg (5mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD KIDNEY, URETER, AND BLADDER: HEMATURIA |
National Technical Information Service. Vol. OTS0571119 |
Consensus Reports:
SAFETY PROFILE:
Safety Information about Methanesulfonyl chloride (CAS NO.124-63-0):
Hazard Codes: T+T,
C
Risk Statements: 24/25-26-34-37-35-22-41
R22: Harmful if swallowed.
R24/25: Toxic in contact with skin and if swallowed
R26: Very toxic by inhalation.
R34: Causes burns.
R35: Causes severe burns.
R37: Irritating to respiratory system
R41: Risk of serious damage to the eyes.
Safety Statements: 26-28-36/37/39-45-25
S25: Avoid contact with eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28: After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 3246 6.1/PG 1
WGK Germany: 2
RTECS: PB2790000
Hazard Note: Toxic/Corrosive
HazardClass: 6.1
PackingGroup: I
Standards and Recommendations:
Analytical Methods:
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