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Current position:Home > Products > Propargyl alcohol

CAS No.:107-19-7

Name: Propargyl alcohol

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 60mg/kg (60mg/kg)   The Threshold Limit Values Vol. 4, Pg. 346, 1980.
mammal (species unspecified) LC50 inhalation 3gm/m3 (3000mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LD50 oral 50mg/kg (50mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LD50 unreported 53mg/kg (53mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.
mouse LC50 inhalation 2000mg/m3/2H (2000mg/m3) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 97, 1966.
mouse LD50 oral 50mg/kg (50mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BLOOD: HEMORRHAGE
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 97, 1966.
rabbit LD50 skin 16mg/kg (16mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4672, 1982.
rabbit LDLo subcutaneous 25mg/kg (25mg/kg)   "Zur Pharmakologie Ungesattigter Alkohole, Dissertation," Bock, H., Pharmakologischen Institu der Universitat Breslau, Poland, 1930Vol. -, Pg. -, 1930.
rat LC50 inhalation 873ppm/2H (873ppm)   GAF Material Safety Data Sheet.
rat LD50 oral 20mg/kg (20mg/kg)   "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4672, 1982.


Consensus Reports:

 


SAFETY PROFILE:

Hazard Codes: ToxicT, DangerousN
Risk Statements: 10-23/24/25-34-51/53-43
10:  Flammable
23/24/25:  Toxic by inhalation, in contact with skin and if swallowed 
34:  Causes burns 
51/53:  Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment 
43:  May cause sensitization by skin contact
Safety Statements: 26-28-36-45-61-28A
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
61:  Avoid release to the environment. Refer to special instructions safety data sheet
RIDADR : UN 2929 6.1/PG 1
WGK Germany : 2
RTECS : UK5075000
HazardClass : 3 
Propargyl alcohol is irritating to skin and mucous membranes.


Standards and Recommendations:

 


Analytical Methods:

 


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