CAS No.:107-19-7
Name: Propargyl alcohol
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | oral | 60mg/kg (60mg/kg) | The Threshold Limit Values Vol. 4, Pg. 346, 1980. | |
mammal (species unspecified) | LC50 | inhalation | 3gm/m3 (3000mg/m3) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988. | |
mammal (species unspecified) | LD50 | oral | 50mg/kg (50mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988. | |
mammal (species unspecified) | LD50 | unreported | 53mg/kg (53mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986. | |
mouse | LC50 | inhalation | 2000mg/m3/2H (2000mg/m3) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 97, 1966. |
mouse | LD50 | oral | 50mg/kg (50mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BLOOD: HEMORRHAGE |
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 97, 1966. |
rabbit | LD50 | skin | 16mg/kg (16mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4672, 1982. |
rabbit | LDLo | subcutaneous | 25mg/kg (25mg/kg) | "Zur Pharmakologie Ungesattigter Alkohole, Dissertation," Bock, H., Pharmakologischen Institu der Universitat Breslau, Poland, 1930Vol. -, Pg. -, 1930. | |
rat | LC50 | inhalation | 873ppm/2H (873ppm) | GAF Material Safety Data Sheet. | |
rat | LD50 | oral | 20mg/kg (20mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4672, 1982. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: T, N
Risk Statements: 10-23/24/25-34-51/53-43
10: Flammable
23/24/25: Toxic by inhalation, in contact with skin and if swallowed
34: Causes burns
51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
43: May cause sensitization by skin contact
Safety Statements: 26-28-36-45-61-28A
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
61: Avoid release to the environment. Refer to special instructions safety data sheet
RIDADR : UN 2929 6.1/PG 1
WGK Germany : 2
RTECS : UK5075000
HazardClass : 3
Propargyl alcohol is irritating to skin and mucous membranes.
Standards and Recommendations:
Analytical Methods:
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