CAS No.:156-51-4

TOXICITY DATA with REFERENCE：

1.		mma-sat 800 µg/plate		NEZAAQ    Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. 33 (1978),474.
2.		dnr-esc 4300 nmol/plate		JTEHD6    Journal of Toxicology and Environmental Health. 9 (1982),287.
3.		orl-mus TDLo:28 g/kg/77W-C:NEO		CNREA8    Cancer Research. 36 (1976),917.
4.		orl-hmn TDLo:1070 µg/kg/D:CNS,GIT,CVS		34ZIAG    Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,461.
5.		orl-man TDLo:46 mg/kg/10W-I:LIV,		AJMEAZ    American Journal of Medicine. 80 (1986),689.
6.		orl-wmn TDLo:18 mg/kg		ANASAB    Anaesthesia. 41 (1986),53.
7.		orl-rat LD50:210 mg/kg		ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),899.
8.		orl-mus LD50:156 mg/kg		ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),899.
9.		ipr-mus LD50:162 mg/kg		JMCMAR    Journal of Medicinal Chemistry. 18 (1975),20.
10.		scu-mus LD50:125 mg/kg		JOENAK    Journal of Endocrinology. 30 (1964),205.

Consensus Reports：

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 312.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 ,1980,p. 175.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 ,1980,p. 175.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

SAFETY PROFILE：

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: wakefulness, blood pressure lowering, constipation, hepatitis, fibrous hepatitis. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. Used as a drug for the treatment of depression. When heated to decomposition it emits very toxic fumes of SO_x and NO_x.
Hazard Codes Xn
Risk Statements 22
R22:Harmful if swallowed.
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS MV8750000
HazardClass 6.1(b)
PackingGroup III

Standards and Recommendations：

 

Analytical Methods：