CAS No.:500-92-5
Name: 1-(p-Chlorophenyl)-5-isopropylbiguanide
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| chicken | LDLo | intravenous | 60mg/kg (60mg/kg) | Compilation of LD50 Values of New Drugs. | |
| chicken | LDLo | oral | 400mg/kg (400mg/kg) | Compilation of LD50 Values of New Drugs. | |
| mouse | LD50 | intravenous | 22mg/kg (22mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 4, Pg. 14, 1949. | |
| mouse | LDLo | intraperitoneal | 25mg/kg (25mg/kg) | Compilation of LD50 Values of New Drugs. | |
| mouse | LDLo | oral | 50mg/kg (50mg/kg) | Compilation of LD50 Values of New Drugs. | |
| rabbit | LD50 | intraperitoneal | 50mg/kg (50mg/kg) | Compilation of LD50 Values of New Drugs. | |
| rabbit | LD50 | oral | 150mg/kg (150mg/kg) | Compilation of LD50 Values of New Drugs. | |
| rat | LD50 | intraperitoneal | 15mg/kg (15mg/kg) | "International Congress of Chemotherapy, Proceedings of the 3rd Congress, 1963," Kuemmerle, H.P., and Prezios, P., Stuttgart, Fed. Rep. Ger., Georg Thieme Verlag, 1964Vol. -, Pg. 367, 1964. | |
| rat | LDLo | intravenous | 40mg/kg (40mg/kg) | Compilation of LD50 Values of New Drugs. |
Consensus Reports：
SAFETY PROFILE：
Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl− and NOx.
Standards and Recommendations：
Analytical Methods：
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