CAS No.:64-65-3

TOXICITY DATA with REFERENCE：

1.		orl-wmn TDLo:100 mg/kg:CNS		LANCAO    Lancet. 2 (1956),967.
2.		orl-man TDLo:20 mg/kg:CNS		LANCAO    Lancet. 2 (1956),967.
3.		ipr-rat LD50:24 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),9.
4.		scu-rat LD50:31 mg/kg		JPPMAB    Journal of Pharmacy and Pharmacology. 13 (1961),244.
5.		ivn-rat LD50:16 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),9.
6.		orl-mus LD50:41 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
7.		ipr-mus LD50:25 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
8.		scu-mus LD50:27 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
9.		ivn-mus LD50:16 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),9.
10.		ims-mus LD50:33 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutic

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Poison by ingestion, intravenous, intraperitoneal, intramuscular, subcutaneous, and parenteral routes. Human systemic effects by ingestion: wakefulness, hallucinations, distorted perceptions, toxic psychosis. An analeptic, central nervous system stimulant; used to counteract barbiturate poisoning. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: T
Risk Statements: 23/24/25
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed
Safety Statements: 22-36/37/39-45 
S22:Do not breathe dust 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible)
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: MA4550000
HazardClass: 6.1(a)
PackingGroup: II

Standards and Recommendations：

 

Analytical Methods：