CAS No.:55-55-0
Name: 4-Methylaminophenol sulfate
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | skin | > 1gm/kg (1000mg/kg) | Kodak Company Reports. Vol. 21MAY1971, | |
| guinea pig | LD50 | unreported | 1585mg/kg (1585mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(9), Pg. 87, 1984. |
| mouse | LD50 | oral | 565mg/kg (565mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION |
National Technical Information Service. Vol. OTS0570966, |
| mouse | LD50 | unreported | 769mg/kg (769mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(9), Pg. 87, 1984. |
| rat | LD50 | unreported | 705mg/kg (705mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(9), Pg. 87, 1984. |
| rat | LDLo | intraperitoneal | 50mg/kg (50mg/kg) | Kodak Company Reports. Vol. 21MAY1971, | |
| rat | LDLo | oral | 200mg/kg (200mg/kg) | Kodak Company Reports. Vol. 21MAY1971, |
Consensus Reports:
Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
SAFETY PROFILE:
Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Hazard Codes:
Xn,
N
Risk Statements: 22-43-48/22-50/53
R22: Harmful if swallowed.
R43: May cause sensitization by skin contact.
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed.
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 36/37-46-60-61
S36/37: Wear suitable protective clothing and gloves.
S46: If swallowed, seek medical advice immediately and show this container or label.
S60: This material and its container must be disposed of as hazardous waste.
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3077 9/PG 3
WGK Germany: 3
RTECS: SL8650000
HazardClass: 6.1
PackingGroup: III
Standards and Recommendations:
Analytical Methods:
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