CAS No.:

TOXICITY DATA with REFERENCE：

1.		unr-hmn TDLo:405 µg/kg:CNS,GIT,BLD		INNDDK    Investigational New Drugs. The Journal of New Anticancer Agents. 1 (1983),169.
2.		orl-rat LDLo:300 mg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),259.
3.		ipr-rat LD50:20,300 µg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),259.
4.		scu-rat LD50:21,760 µg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),259.
5.		ivn-rat LD50:18,070 µg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),259.
6.		orl-mus LD50:419 mg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),250.
7.		ipr-mus LD50:13,900 µg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),250.
8.		scu-mus LD50:16,900 µg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),250.
9.		ivn-mus LD50:14 mg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),250.
10.		ivn-dog LDLo:1 mg/kg		JJANAX    Japanese Journal of Antibiotics. 39 (1986),265.

SAFETY PROFILE：
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by an unspecified route: anorexia, nausea or vomiting, and leukopenia. An experimental teratogen. Experimental reproductive effects. Used as an anticancer agent. When heated to decomposition it emits toxic fumes of NO_x and HCl.