Current position:Home > Products > 7-Chloro-10-(3-dimethylaminopropyl)-benzo-(b)(1,8)-5(10H)-naphthayridone hydrochloride
CAS No.:28907-45-1
Name: 7-Chloro-10-(3-dimethylaminopropyl)-benzo-(b)(1,8)-5(10H)-naphthayridone hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 106mg/kg (106mg/kg) | Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 503, 1975. | |
| mouse | LD50 | intravenous | 33mg/kg (33mg/kg) | Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 121, 1975. | |
| mouse | LD50 | oral | 200mg/kg (200mg/kg) | Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 121, 1975. | |
| rabbit | LD50 | intravenous | 12mg/kg (12mg/kg) | Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 503, 1975. | |
| rat | LD50 | intraperitoneal | 105mg/kg (105mg/kg) | Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 503, 1975. | |
| rat | LD50 | intravenous | 33mg/kg (33mg/kg) | Polish Journal of Pharmacology and Pharmacy. Vol. 29, Pg. 23, 1977. | |
| rat | LD50 | oral | 500mg/kg (500mg/kg) | Polish Journal of Pharmacology and Pharmacy. Vol. 27, Pg. 503, 1975. | |
| rat | LD50 | subcutaneous | 136mg/kg (136mg/kg) | Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 34, Pg. 115, 1977. |
Consensus Reports：
SAFETY PROFILE：
Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
Standards and Recommendations：
Analytical Methods：
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