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Current position:Home > Products > Bis(2-hydroxyethyl)-2-(2-chloroethylthio)ethylsulfonium, chloride

CAS No.:64036-91-5

Name: Bis(2-hydroxyethyl)-2-(2-chloroethylthio)ethylsulfonium, chloride

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 6mg/kg (6mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
dog LD50 skin > 30mg/kg (30mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
mouse LD50 intraperitoneal 1200ug/kg (1.2mg/kg)   Journal of Organic Chemistry. Vol. 11, Pg. 704, 1946.
mouse LD50 skin 15mg/kg (15mg/kg) GASTROINTESTINAL: OTHER CHANGES

LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"

ENDOCRINE: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
mouse LDLo subcutaneous 25mg/kg (25mg/kg)   National Technical Information Service. Vol. PB158-507,
rabbit LD50 intravenous 4500ug/kg (4.5mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
rabbit LD50 skin > 30mg/kg (30mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
rat LD50 skin 10mg/kg (10mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.


Consensus Reports:

 


SAFETY PROFILE:

A poison by skin contact, subcutaneous, and intravenous routes. See also SULFONATES. When heated to decomposition it emits very toxic fumes of Cl and SOx.


Standards and Recommendations:

 


Analytical Methods:

 


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