Current position:Home > Products > Bis(2-hydroxyethyl)-2-(2-chloroethylthio)ethylsulfonium, chloride
CAS No.:64036-91-5
Name: Bis(2-hydroxyethyl)-2-(2-chloroethylthio)ethylsulfonium, chloride
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | 6mg/kg (6mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948. | |
| dog | LD50 | skin | > 30mg/kg (30mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948. | |
| mouse | LD50 | intraperitoneal | 1200ug/kg (1.2mg/kg) | Journal of Organic Chemistry. Vol. 11, Pg. 704, 1946. | |
| mouse | LD50 | skin | 15mg/kg (15mg/kg) | GASTROINTESTINAL: OTHER CHANGES LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" ENDOCRINE: OTHER CHANGES |
Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948. |
| mouse | LDLo | subcutaneous | 25mg/kg (25mg/kg) | National Technical Information Service. Vol. PB158-507, | |
| rabbit | LD50 | intravenous | 4500ug/kg (4.5mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948. | |
| rabbit | LD50 | skin | > 30mg/kg (30mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948. | |
| rat | LD50 | skin | 10mg/kg (10mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948. |
Consensus Reports:
SAFETY PROFILE:
A poison by skin contact, subcutaneous, and intravenous routes. See also SULFONATES. When heated to decomposition it emits very toxic fumes of Cl− and SOx.
Standards and Recommendations:
Analytical Methods:
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