CAS No.:331-39-5

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	> 721mg/kg (721mg/kg)		Yakugaku Zasshi. Journal of Pharmacy. Vol. 104, Pg. 793, 1984.
rat	LDLo	intraperitoneal	1500mg/kg (1500mg/kg)		Toxicology and Applied Pharmacology. Vol. 36, Pg. 227, 1976.

Caffeic acid (CAS NO.331-39-5) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.

Consensus Reports：

 

SAFETY PROFILE：

Moderately toxic by intraperitoneal route. An experimental teratogen. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes.
Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-40-63-68
R36/37/38:Irritating to eyes, respiratory system and skin. 
R40:Limited evidence of a carcinogenic effect. 
R63:Possible risk of harm to the unborn child. 
R68:Possible risk of irreversible effects.
Safety Statements: 26-36/37/39-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.

Standards and Recommendations：

 

Analytical Methods：