CAS No.:25387-67-1
Name: Camptothecin, sodium salt
Details Introduction
TOXICITY DATA with REFERENCE:
| 1. |
ivn-hmn TDLo:2500 µg/kg/7D-I:BLD |
CCROBU Cancer Chemotherapy Reports, Part 1. 56 (1972),515. | ||
| 2. |
orl-mus LD50:27 mg/kg |
PMDCAY Progress in Medical Chemistry. 9 (1973),1. | ||
| 3. |
ivn-mus LD50:57 mg/kg |
PMDCAY Progress in Medical Chemistry. 9 (1973),1. |
Consensus Reports:
SAFETY PROFILE:
Poison by ingestion and intravenous routes. Human systemic effects by intravenous route: reduction in the number of white blood cells (leukopenia), reduction in the number of blood platelets (thrombocytopenia), and changes in blood cell count. When heated to decomposition, Camptothecin, sodium salt (CAS NO.25387-67-1) emits toxic fumes of NOx and Na2O.
Standards and Recommendations:
Analytical Methods:
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