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CAS No.:4213-44-9

Name: Chloroquine mustard

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 200ug/kg (0.2mg/kg) BLOOD: OTHER CHANGES Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 202, 1965.
monkey LDLo intravenous 410ug/kg (0.41mg/kg) BLOOD: OTHER CHANGES Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 202, 1965.
mouse LD50 intraperitoneal 7mg/kg (7mg/kg)   Cancer Research. Vol. 21, Pg. 1124, 1961.
rat LD10 intraperitoneal 1100ug/kg (1.1mg/kg)   Cancer Chemotherapy Reports. Vol. 17, Pg. 63, 1962.


Consensus Reports:

 


SAFETY PROFILE:

A deadly poison by intraperitoneal and intravenous routes. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. When  Chloroquine mustard (CAS NO.4213-44-9) is heated to decomposition ,it emits very toxic fumes of Cl− and NOx. See also CHLOROQUINE.


Standards and Recommendations:

 


Analytical Methods:

 


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