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Current position:Home > Products > DIBEKACIN

CAS No.:34493-98-6

Name: DIBEKACIN

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 373mg/kg (373mg/kg)   Journal of Pharmacobio-Dynamics. Vol. 4, Pg. 356, 1981.
mouse LD50 intraperitoneal 11960ug/kg (11.96mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 119, 1975.
mouse LD50 intravenous 8950ug/kg (8.95mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 119, 1975.
mouse LD50 oral 763mg/kg (763mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 119, 1975.
mouse LD50 subcutaneous 15980ug/kg (15.98mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 119, 1975.
rat LD50 intraperitoneal 16760ug/kg (16.76mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 119, 1975.
rat LD50 intravenous 12510ug/kg (12.51mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 119, 1975.
rat LD50 oral > 6950mg/kg (6950mg/kg)   Japanese Journal of Antibiotics. Vol. 26, Pg. 221, 1973.
rat LD50 subcutaneous 23870ug/kg (23.87mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 119, 1975.


Consensus Reports:

EPA Genetic Toxicology Program.


SAFETY PROFILE:

Poison by intraperitoneal, subcutaneous, intramuscular, and intravenous routes. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. An antibacterial agent. When heated to decomposition it emits toxic fumes of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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