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CAS No.:89-25-8

Name: Edaravone

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

eye-rbt 500 mg/24H MOD

    28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,144.
2.    

orl-rat LD50:3500 mg/kg

    LONZA#    Personal Communication from LONZA Ltd., CH-4002, Basel, Switzerland, to NIOSH, Cincinnati, OH 45226 08FEB79 .
3.    

ipr-mus LD50:2012 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 36 (1973),27.

 


Consensus Reports:

NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-141 ,1978. . Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Moderately toxic by ingestion and intraperitoneal routes. An eye irritant. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of Norphenazone (CAS NO.89-25-8):
Hazard Codes: Xi
Risk Statements: 36/37/38:  Irritating to eyes, respiratory system and skin 
Safety Statements: 26-36
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing 
WGK Germany: 1


Standards and Recommendations:

 


Analytical Methods:

 


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