CAS No.:107-22-2

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	300uL/kg (0.3mL/kg)		National Technical Information Service. Vol. OTS0535072,
guinea pig	LD50	oral	760mg/kg (760mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES	Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
guinea pig	LD50	oral	10gm/kg (10000mg/kg)		National Technical Information Service. Vol. OTS0538086,
guinea pig	LD50	skin	6600mg/kg (6600mg/kg)		"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 291, 1969.
mouse	LD50	intraperitoneal	200mg/kg (200mg/kg)		National Technical Information Service. Vol. AD438-895,
mouse	LD50	oral	400mg/kg (400mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS	National Technical Information Service. Vol. OTS0533618,
mouse	LD50	oral	1280mg/kg (1280mg/kg)		National Technical Information Service. Vol. OTS0538086,
rabbit	LD50	intraperitoneal	60mg/kg (60mg/kg)		National Technical Information Service. Vol. OTS0535072,
rabbit	LD50	intravenous	60mg/kg (60mg/kg)		National Technical Information Service. Vol. OTS0535072,
rabbit	LD50	oral	> 3175mg/kg (3175mg/kg)		National Technical Information Service. Vol. OTS0538086,
rabbit	LD50	skin	10mL/kg (10mL/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" LIVER: OTHER CHANGES	National Technical Information Service. Vol. OTS0535072,
rabbit	LD50	skin	10mL/kg (10mL/kg)		Union Carbide Data Sheet. Vol. 11/4/1971,
rabbit	LD50	skin	10mL/kg (10mL/kg)		Union Carbide Data Sheet. Vol. 11/12/1965,
rat	LC50	inhalation	2410mg/m3/4H (2410mg/m3)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION LUNGS, THORAX, OR RESPIRATION: DYSPNEA	National Technical Information Service. Vol. OTS0535127,
rat	LD50	oral	200mg/kg (200mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS	National Technical Information Service. Vol. OTS0533618,
rat	LD50	oral	2960mg/kg (2960mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	National Technical Information Service. Vol. OTS0535124,
rat	LD50	oral	4290mg/kg (4290mg/kg)		Union Carbide Data Sheet. Vol. 11/4/1971,
rat	LD50	skin	> 2gm/kg (2000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	National Technical Information Service. Vol. OTS0535506,
rat	LDLo	intraperitoneal	100mg/kg (100mg/kg)		National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 9, 1953.

Consensus Reports：

Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Safety Information of Glyoxal (CAS NO.107-22-2):
Hazard Codes: Xn
Risk Statements: 20-36/38-43-68  
R20:Harmful by inhalation. 
R36/38:Irritating to eyes and skin. 
R43:May cause sensitization by skin contact. 
R68:Possible risk of irreversible effects.
Safety Statements: 36/37
S36/37:Wear suitable protective clothing and gloves.
RIDADR: UN 1760
WGK Germany: 1
RTECS: MD2700000

Standards and Recommendations：

ACGIH TLV: TWA 0.1 mg/m³ (sensitizer); Not Classifiable as a Human Carcinogen).

Analytical Methods：