CAS No.:10075-36-2
Name: Isoaminile cyclamate
Details Introduction
TOXICITY DATA with REFERENCE:
| dog | LD50 | intravenous | 84mg/kg (84mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 323, 1968. |
| mouse | LD50 | intraperitoneal | 133mg/kg (133mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 323, 1968. |
| mouse | LD50 | intravenous | 57mg/kg (57mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Kiso to Rinsho. Clinical Report. Vol. 5, Pg. 2212, 1971. |
| mouse | LD50 | oral | 298mg/kg (298mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Kiso to Rinsho. Clinical Report. Vol. 5, Pg. 2212, 1971. |
| mouse | LD50 | subcutaneous | 175mg/kg (175mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA |
Kiso to Rinsho. Clinical Report. Vol. 5, Pg. 1787, 1971. |
| rat | LD50 | oral | 270mg/kg (270mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Kiso to Rinsho. Clinical Report. Vol. 5, Pg. 2212, 1971. |
| rat | LD50 | subcutaneous | 138mg/kg (138mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Kiso to Rinsho. Clinical Report. Vol. 5, Pg. 2212, 1971. |
Consensus Reports:
Cyanide and its compounds are on the Community Right-To-Know List.
SAFETY PROFILE:
Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of SOx, CN−, and NOx.
Standards and Recommendations:
Analytical Methods:
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