CAS No.:51013-18-4
Name: Methyl-2-pyrrolidinone
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 4400mg/kg (4400mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(6), Pg. 84, 1970. | |
| mouse | LD50 | intraperitoneal | 2310mg/kg (2310mg/kg) | Yokohama Igaku. Yokohama Medicine. Vol. 31, Pg. 327, 1980. | |
| mouse | LDLo | oral | 3gm/kg (3000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: OTHER CHANGES BLOOD: CHANGES IN SPLEEN |
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 27, 1965. |
| rabbit | LD50 | oral | 3500mg/kg (3500mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(6), Pg. 84, 1970. | |
| rat | LDLo | oral | 3gm/kg (3000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: FATTY LIVER DEGERATION BLOOD: CHANGES IN SPLEEN |
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 27, 1965. |
Consensus Reports：
SAFETY PROFILE：
Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx.
Standards and Recommendations：
Analytical Methods：
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