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Current position:Home > Products > Methyl phenidyl acetate

CAS No.:113-45-1

Name: Methyl phenidyl acetate

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

ipr-mus TDLo:200 mg/kg (10D preg):TER

    CAJPBD    Proceedings of the Congenital Anomalies Research Association of Japan. 3 (1963),2.
2.    

orl-cld TDLo:180 mg/kg/26W-I

    AJPSAO    American Journal of Psychiatry. 143 (1985),1176.
3.    

ivn-man LDLo:445 mg/kg/34W-I:PUL

    HPCQA4    Human Pathology. 3 (1972),67.
4.    

ipr-rat LD50:430 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 17 (1960),121.
5.    

orl-mus LD50:190 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 131 (1961),115.
6.    

ipr-mus LD50:32 mg/kg

    JNPHAG    Journal de Pharmacologie. (Masson Publishing USA, Inc. 17 (1986),37.
7.    

scu-mus LD50:218 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 184 (1970),34.
8.    

ivn-mus LD50:41 mg/kg

    BCPCA6    Biochemical Pharmacology. 8 (1961),263.

Consensus Reports:

 


SAFETY PROFILE:

Poison experimentally by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic to humans by intravenous route. Human systemic effects by intravenous route: dyspnea. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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