CAS No.:113-45-1
Name: Methyl phenidyl acetate
Details Introduction
TOXICITY DATA with REFERENCE:
| 1. |
ipr-mus TDLo:200 mg/kg (10D preg):TER |
CAJPBD Proceedings of the Congenital Anomalies Research Association of Japan. 3 (1963),2. | ||
| 2. |
orl-cld TDLo:180 mg/kg/26W-I |
AJPSAO American Journal of Psychiatry. 143 (1985),1176. | ||
| 3. |
ivn-man LDLo:445 mg/kg/34W-I:PUL |
HPCQA4 Human Pathology. 3 (1972),67. | ||
| 4. |
ipr-rat LD50:430 mg/kg |
APTOA6 Acta Pharmacologica et Toxicologica. 17 (1960),121. | ||
| 5. |
orl-mus LD50:190 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 131 (1961),115. | ||
| 6. |
ipr-mus LD50:32 mg/kg |
JNPHAG Journal de Pharmacologie. (Masson Publishing USA, Inc. 17 (1986),37. | ||
| 7. |
scu-mus LD50:218 mg/kg |
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 184 (1970),34. | ||
| 8. |
ivn-mus LD50:41 mg/kg |
BCPCA6 Biochemical Pharmacology. 8 (1961),263. |
Consensus Reports:
SAFETY PROFILE:
Poison experimentally by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic to humans by intravenous route. Human systemic effects by intravenous route: dyspnea. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx.
Standards and Recommendations:
Analytical Methods:
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