CAS No.:110-18-9
Name: N,N,N',N'-Tetramethylethylenediamine
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 630mg/kg (630mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(6), Pg. 55, 1984. | |
| quail | LD50 | oral | > 316mg/kg (316mg/kg) | Ecotoxicology and Environmental Safety. Vol. 6, Pg. 149, 1982. | |
| rabbit | LD50 | skin | 5390mg/kg (5390mg/kg) | American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969. | |
| rabbit | LD50 | subcutaneous | 1230mg/kg (1230mg/kg) | Toxicologist. Vol. 15, Pg. 19, 1995. | |
| rat | LC50 | inhalation | 1318ppm/4H (1318ppm) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ATAXIA BEHAVIORAL: IRRITABILITY |
Toxicologist. Vol. 8, Pg. 249, 1988. |
| rat | LD50 | oral | 268mg/kg (268mg/kg) | BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES SPINAL CORD: OTHER DEGENERATIVE CHANGES |
Toxicologist. Vol. 15, Pg. 19, 1995. |
Consensus Reports:
Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Moderately toxic by ingestion. Mildly toxic by skin contact. A skin and severe eye irritant. Flammable when exposed to heat or flame; can react with oxidizing materials. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
Hazard Codes:
F,
C,
Xi
Risk Statements: 11-20/22-34-20/21/22
R11:Highly flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R20/22:Harmful by inhalation and if swallowed.
R34:Causes burns.
Safety Statements: 16-26-36/37/39-45
S16:Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Standards and Recommendations:
DOT Classification: 3; Label: Flammable Liquid
Analytical Methods:
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