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CAS No.:20170-20-1

Name: Pasalin

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1390mg/kg (1390mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
mouse LD50 oral 960mg/kg (960mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Gifu Daigaku Igakubu Kiyo. Papers of the Gifu University School of Medicine. Vol. 20, Pg. 360, 1972.
mouse LD50 subcutaneous 15200mg/kg (15200mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
rat LD50 intraperitoneal 1480mg/kg (1480mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
rat LD50 oral 815mg/kg (815mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Gifu Daigaku Igakubu Kiyo. Papers of the Gifu University School of Medicine. Vol. 20, Pg. 360, 1972.
rat LD50 subcutaneous > 12819mg/kg (12819mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.


Consensus Reports:

 


SAFETY PROFILE:

Moderately toxic by intraperitoneal and ingestion routes. An analgesic and anti-inflammatory agent. When Pasalin (CAS NO.20170-20-1) is heated to decomposition, it emits toxic fumes of NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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