CAS No.:27591-69-1

TOXICITY DATA with REFERENCE：

1.		dnd-esc 20 µmol/L		MUREAV    Mutation Research. 89 (1981),95.
2.		dni-mus:leu 14,600 µg/L		INNDDK    Investigational New Drugs. The Journal of New Anticancer Agents. 1 (1983),103.
3.		orl-hmn TDLo:4 mg/kg:CNS,GIT		CCROBU    Cancer Chemotherapy Reports, Part 1. 57 (1973),209.
4.		orl-rat LD50:852 mg/kg		SCIEAS    Science. 169 (1970),1213.
5.		ipr-rat LD50:244 mg/kg		SCIEAS    Science. 169 (1970),1213.
6.		orl-mus LD50:959 mg/kg		SCIEAS    Science. 169 (1970),1213.
7.		ipr-mus LD50:145 mg/kg		SCIEAS    Science. 169 (1970),1213.

Consensus Reports：

 

SAFETY PROFILE：

Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Human systemic effects by ingestion: somnolence, anorexia, hypermotility and diarrhea. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NO_x.Safety information of Tilorone dihydrochloride (CAS NO.27591-69-1):
Hazard Codes:  Xn
Risk Statements:
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
40: Limited evidence of a carcinogenic effect
Safety Statements:
7: Keep container tightly closed
22: Do not breathe dust
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37/39: Wear suitable gloves and eye/face protection
WGK Germany: 3
RTECS: LL9000000

Standards and Recommendations：

 

Analytical Methods：