CAS No.:59917-39-4
Name: Vindesine sulfate
Details Introduction
TOXICITY DATA with REFERENCE:
| mouse | LD50 | intraperitoneal | 3500ug/kg (3.5mg/kg) | BEHAVIORAL: ATAXIA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED |
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983. |
| mouse | LD50 | intravenous | 6300ug/kg (6.3mg/kg) | Journal of Toxicology and Environmental Health. Vol. 1, Pg. 843, 1976. | |
| mouse | LD50 | subcutaneous | 6800ug/kg (6.8mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983. | |
| rat | LD50 | intraperitoneal | 1050ug/kg (1.05mg/kg) | BEHAVIORAL: ATAXIA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED |
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983. |
| rat | LD50 | intravenous | 1920ug/kg (1.92mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BLOOD: NORMOCYTIC ANEMIA KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED |
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983. |
| rat | LD50 | subcutaneous | 1790ug/kg (1.79mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983. |
Consensus Reports:
SAFETY PROFILE:
Poison by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
Hazard codes:
Xn Harmful
Risk statements: 40 Limited evidence of a carcinogenic effect.
Safety statements: 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
36 Wear suitable protective clothing.
Standards and Recommendations:
Analytical Methods:
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