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Current position:Home > Products > Vindesine sulfate

CAS No.:59917-39-4

Name: Vindesine sulfate

Details Introduction

TOXICITY DATA with REFERENCE:

mouse LD50 intraperitoneal 3500ug/kg (3.5mg/kg) BEHAVIORAL: ATAXIA
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.
mouse LD50 intravenous 6300ug/kg (6.3mg/kg)   Journal of Toxicology and Environmental Health. Vol. 1, Pg. 843, 1976.
mouse LD50 subcutaneous 6800ug/kg (6.8mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.
rat LD50 intraperitoneal 1050ug/kg (1.05mg/kg) BEHAVIORAL: ATAXIA
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.
rat LD50 intravenous 1920ug/kg (1.92mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BLOOD: NORMOCYTIC ANEMIA
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.
rat LD50 subcutaneous 1790ug/kg (1.79mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.


Consensus Reports:

 


SAFETY PROFILE:

Poison by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.

Hazard codes: Xn Harmful
Risk statements: 40 Limited evidence of a carcinogenic effect. 
Safety statements: 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
                           36 Wear suitable protective clothing. 


Standards and Recommendations:

 


Analytical Methods:

 


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