CAS No.:122-34-9
Name: Simazine
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| chicken | LD50 | oral | > 5gm/kg (5000mg/kg) | "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A369, Pg. 1984, | |
| mammal (species unspecified) | LD50 | oral | 2014mg/kg (2014mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) |
National Technical Information Service. Vol. PB288-416, |
| mammal (species unspecified) | LD50 | unreported | 1400mg/kg (1400mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 44(6), Pg. 81, 1979. | |
| mouse | LD50 | intravenous | 100mg/kg (100mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04003, | |
| mouse | LDLo | oral | 5gm/kg (5000mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 27(8), Pg. 22, 1962. |
| pigeon | LD50 | oral | > 5gm/kg (5000mg/kg) | "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A369, Pg. 1984, | |
| rabbit | LD50 | oral | > 5gm/kg (5000mg/kg) | "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A369, Pg. 1984, | |
| rabbit | LD50 | skin | > 10200mg/kg (10200mg/kg) | Yakkyoku. Pharmacy. Vol. 37, Pg. 427, 1986. | |
| rat | LC50 | inhalation | 9800mg/m3/4H (9800mg/m3) | Farm Chemicals Handbook. Vol. -, Pg. C275, 1991. | |
| rat | LD50 | oral | 971mg/kg (971mg/kg) | Fundamental and Applied Toxicology. Vol. 7, Pg. 299, 1986. | |
| rat | LD50 | skin | > 5gm/kg (5000mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 15, Pg. 315, 1990. | |
| rat | LD50 | unreported | 1390mg/kg (1390mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 7(5), Pg. 54, 1963. |
Consensus Reports:
SAFETY PROFILE:
Standards and Recommendations:
Analytical Methods:
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